Assemblies
Assembly Name:
RAF proto-oncogene serine/threonine-protein kinase
Multimeric state:
homo dimer
Accessible surface area:
25796.84 Å2
Buried surface area:
2536.89 Å2
Dissociation area:
1,268.45
Å2
Dissociation energy (ΔGdiss):
-0.6
kcal/mol
Dissociation entropy (TΔSdiss):
13.43
kcal/mol
Symmetry number:
2
PDBe Complex ID:
PDB-CPX-137339
Macromolecules
Chains: A, B
Length: 307 amino acids
Theoretical weight: 35.43 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Pfam: Protein kinase domain
InterPro:
Length: 307 amino acids
Theoretical weight: 35.43 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
P04049 (Residues: 323-618; Coverage: 46%)
Pfam: Protein kinase domain
InterPro:
- Protein kinase-like domain superfamily
- Protein kinase domain
- Serine-threonine/tyrosine-protein kinase, catalytic domain
- Protein kinase, ATP binding site
- Serine/threonine-protein kinase, active site
