PDBe 3omv

X-ray diffraction
4Å resolution

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein. 
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
RAF proto-oncogene serine/threonine-protein kinase Chains: A, B
Molecule details ›
Chains: A, B
Length: 307 amino acids
Theoretical weight: 35.43 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P04049 (Residues: 323-618; Coverage: 46%)
Gene names: RAF, RAF1
Sequence domains: Protein tyrosine kinase
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E SUPERBRIGHT
Spacegroup: P41212
Unit cell:
a: 99.57Å b: 99.57Å c: 161.422Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.283 0.28 0.364
Expression system: Spodoptera frugiperda