› 3olp

X-ray diffraction
1.95Å resolution

Crystal structure of a bacterial phosphoglucomutase, an enzyme important in the virulence of multiple human pathogens

Released:
DOI: 10.2210/pdb3olp/pdb
PDB entry 3olp coloured by chain, front view.
PDB entry 3olp coloured by chain, side view.
PDB entry 3olp coloured by chain, top view.
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium
Primary publication:
Crystal structure of a bacterial phosphoglucomutase, an enzyme involved in the virulence of multiple human pathogens.
Mehra-Chaudhary R, Mick J, Tanner JJ, Henzl MT, Beamer LJ
Proteins 79 1215-29 (2011)
PMID: 21246636

Function and Biology Details

Reaction catalysed: 
Alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-187366 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:

Ligands and Environments

2 bound ligands:
Ligand MG 2 x MG
Ligand PO4 2 x PO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P21
Unit cell:
a: 58.125Å b: 85.125Å c: 111.879Å
α: 90° β: 94.42° γ: 90°
R-values:
R R work R free
0.167 0.166 0.195
Expression system: Escherichia coli BL21(DE3)

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Citations

2 review citations

Biocatalytic Phosphorylations of Metabolites: Past, Present, and Future.
Wohlgemuth et al. (2017)
1 more

2 mentions without citation

Crystal structure of a bacterial phosphoglucomutase, an enzyme involved in the virulence of multiple human pathogens.
Mehra-Chaudhary et al. (2011)
1 more