PDBe 3od6

X-ray diffraction
2.68Å resolution

Crystal structure of p38alpha Y323T active mutant


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Mitogen-activated protein kinase 14 Chain: X
Molecule details ›
Chain: X
Length: 360 amino acids
Theoretical weight: 41.28 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q16539 (Residues: 1-360; Coverage: 100%)
  • Best match: Q16539-3 (Residues: 1-280)
Gene names: CSBP, CSBP1, CSBP2, CSPB1, MAPK14, MXI2, SAPK2A
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P21
Unit cell:
a: 40.332Å b: 71.766Å c: 70.96Å
α: 90° β: 90.28° γ: 90°
R R work R free
0.215 0.199 0.283
Expression system: Escherichia coli