3obv

X-ray diffraction
2.75Å resolution

Autoinhibited Formin mDia1 Structure

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-126686 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Protein diaphanous homolog 1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 327 amino acids
Theoretical weight: 37.72 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: O08808 (Residues: 131-457; Coverage: 26%)
Gene names: Diap1, Diaph1
Sequence domains:
Structure domains:
Protein diaphanous homolog 1 Chains: E, F, G, H
Molecule details ›
Chains: E, F, G, H
Length: 457 amino acids
Theoretical weight: 53.07 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: O08808 (Residues: 753-1209; Coverage: 36%)
Gene names: Diap1, Diaph1
Sequence domains: Formin Homology 2 Domain
Structure domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: GLC, FRU
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P21
Unit cell:
a: 93.926Å b: 208.519Å c: 131.516Å
α: 90° β: 102.74° γ: 90°
R-values:
R R work R free
0.2 0.199 0.261
Expression system: Escherichia coli