PDBe 3o5z

X-ray diffraction
2.01Å resolution

Crystal structure of the SH3 domain from p85beta subunit of phosphoinositide 3-kinase (PI3K)

Released:
Source organism: Homo sapiens
Primary publication:
X-ray structure of the SH3 domain of the phosphoinositide 3-kinase p85β subunit.
Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 67 1328-33 (2011)
PMID: 22102226

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phosphatidylinositol 3-kinase regulatory subunit beta Chains: A, B
Molecule details ›
Chains: A, B
Length: 90 amino acids
Theoretical weight: 9.81 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O00459 (Residues: 1-85; Coverage: 12%)
Gene name: PIK3R2
Structure domains: SH3 Domains

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X13
Spacegroup: P212121
Unit cell:
a: 46.01Å b: 57.79Å c: 62.97Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.212 0.212 0.259
Expression system: Escherichia coli