› 3o48

X-ray diffraction
1.75Å resolution

Crystal structure of fission protein Fis1 from Saccharomyces cerevisiae

Released:
DOI: 10.2210/pdb3o48/pdb
PDB entry 3o48 coloured by chain, front view.
PDB entry 3o48 coloured by chain, side view.
PDB entry 3o48 coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
The 1.75 Å resolution structure of fission protein Fis1 from Saccharomyces cerevisiae reveals elusive interactions of the autoinhibitory domain.
Tooley JE, Khangulov V, Lees JP, Schlessman JL, Bewley MC, Heroux A, Bosch J, Hill RB
Acta Crystallogr Sect F Struct Biol Cryst Commun 67 1310-5 (2011)
PMID: 22102223

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-154133 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mitochondrial fission 1 protein Chain: A
Molecule details ›
Chain: A
Length: 134 amino acids
Theoretical weight: 15.84 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P40515 (Residues: 1-127; Coverage: 82%)
Gene names: FIS1, MDV2, YIL065C
Sequence domains:
Structure domains: Tetratricopeptide repeat domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X25
Spacegroup: P43212
Unit cell:
a: 46.02Å b: 46.02Å c: 139.22Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.166 0.165 0.188
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

3 citation in other articles

Crystal structure of mitochondrial fission complex reveals scaffolding function for mitochondrial division 1 (Mdv1) coiled coil.
Zhang et al. (2012)
2 more

3 mentions without citation

Molecular Motor Dnm1 Synergistically Induces Membrane Curvature To Facilitate Mitochondrial Fission.
Lee et al. (2017)
2 more