Assemblies
Assembly Name:
GyrA-GyrB DNA Gyrase complex
Multimeric state:
hetero tetramer
Accessible surface area:
79047.85 Å2
Buried surface area:
11285.7 Å2
Dissociation area:
5,467.92
Å2
Dissociation energy (ΔGdiss):
22.71
kcal/mol
Dissociation entropy (TΔSdiss):
45.58
kcal/mol
Symmetry number:
2
PDBe Complex ID:
PDB-CPX-142492
Macromolecules
Chain: A
Length: 525 amino acids
Theoretical weight: 59.66 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli BL21
UniProt:
Pfam: DNA gyrase/topoisomerase IV, subunit A
InterPro:
Length: 525 amino acids
Theoretical weight: 59.66 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli BL21
UniProt:
- Canonical: P0AES4 (Residues: 1-525; Coverage: 60%)
Pfam: DNA gyrase/topoisomerase IV, subunit A
InterPro:
- DNA topoisomerase, type IIA, domain A
- DNA topoisomerase, type IIA-like domain superfamily
- DNA topoisomerase, type IIA, domain A, alpha-beta
- DNA topoisomerase, type IIA, alpha-helical domain superfamily
Chain: B
Length: 420 amino acids
Theoretical weight: 48.23 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli BL21
UniProt:
Pfam:
InterPro:
Length: 420 amino acids
Theoretical weight: 48.23 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli BL21
UniProt:
- Canonical: P0AES6 (Residues: 389-804; Coverage: 52%)
Pfam:
InterPro:
- DNA topoisomerase, type IIA-like domain superfamily
- DNA topoisomerase, type IIA
- DNA topoisomerase, type IIA, subunit B, C-terminal
- TOPRIM domain
- DNA gyrase subunit B, TOPRIM domain
- DNA topoisomerase, type IIA, conserved site
- DNA topoisomerase, type IIA, subunit B
- DNA gyrase subunit B insert domain
- DNA gyrase B subunit, C-terminal