EC 3.5.4.4: Adenosine deaminase
Reaction catalysed:
2'-deoxyadenosine + H(2)O = 2'-deoxyinosine + NH(3)
Systematic name:
Adenosine aminohydrolase
Alternative Name(s):
- Deoxyadenosine deaminase
GO terms
Biochemical function:
Biological process:
- inhibition of non-skeletal tissue mineralization
- negative regulation of mucus secretion
- mucus secretion
- negative regulation of thymocyte apoptotic process
- thymocyte apoptotic process
- negative regulation of penile erection
- negative regulation of adenosine receptor signaling pathway
- leukocyte migration
- positive regulation of T cell activation
- positive regulation of T cell receptor signaling pathway
- T cell receptor signaling pathway
- positive regulation of calcium-mediated signaling
- negative regulation of inflammatory response
- embryonic digestive tract development
- Peyer's patch development
- lung alveolus development
- positive regulation of alpha-beta T cell differentiation
- alpha-beta T cell differentiation
- xanthine biosynthetic process
- inosine biosynthetic process
- hypoxanthine biosynthetic process
- adenosine metabolic process
- dATP catabolic process
- dAMP catabolic process
- positive regulation of smooth muscle contraction
- positive regulation of T cell differentiation
- regulation of T cell differentiation
- AMP salvage
- amide catabolic process
- hypoxanthine salvage
- penile erection
- negative regulation of apoptotic process
- negative regulation of circadian sleep/wake cycle, non-REM sleep
- T cell activation
- B cell proliferation
- regulation of cell-cell adhesion mediated by integrin
- response to vitamin E
- positive regulation of T cell differentiation in thymus
- regulation of T cell differentiation in thymus
- T cell differentiation in thymus
- IMP salvage
- GMP salvage
- purine nucleotide salvage
- positive regulation of B cell proliferation
- lung development
- T cell differentiation
- calcium-mediated signaling
- response to purine-containing compound
- positive regulation of heart rate
- response to inorganic substance
- purine ribonucleoside monophosphate biosynthetic process
- nucleotide metabolic process
- cell adhesion
- smooth muscle contraction
- apoptotic process
- AMP catabolic process
- deoxyadenosine catabolic process
- adenosine catabolic process
- negative regulation of mature B cell apoptotic process
- mature B cell apoptotic process
- negative regulation of leukocyte migration
- positive regulation of germinal center formation
- germinal center formation
- germinal center B cell differentiation
- placenta development
- liver development
- trophectodermal cell differentiation
- histamine secretion
- in utero embryonic development
- response to hypoxia
- allantoin metabolic process
Protein family (Pfam)
InterPro annotations
CATH domain