› 3muj

X-ray diffraction
1.92Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190619 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transcription factor COE3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 138 amino acids
Theoretical weight: 15.25 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9H4W6 (Residues: 261-395; Coverage: 23%)
Gene names: COE3, EBF3
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

2 bound ligands:
Ligand EDO 3 x EDO
Ligand CL 2 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.2
Spacegroup: P65
Unit cell:
a: 134.68Å b: 134.68Å c: 41.15Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.171 0.17 0.193
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

3 review citations

The regulatory network of B-cell differentiation: a focused view of early B-cell factor 1 function.
Boller et al. (2014)
2 more

2 mentions without citation

Structural determination of functional domains in early B-cell factor (EBF) family of transcription factors reveals similarities to Rel DNA-binding proteins and a novel dimerization motif.
Siponen et al. (2010)
1 more