› 3mq3

X-ray diffraction
2.8Å resolution

Crystal structure of native bovine PDP1c

Released:
DOI: 10.2210/pdb3mq3/pdb
PDB entry 3mq3 coloured by chain, front view.
PDB entry 3mq3 coloured by chain, side view.
PDB entry 3mq3 coloured by chain, top view.
Source organism: Bos taurus
Entry authors: Guo Y, Ernst SR, Carroll DW, Hackert ML

Function and Biology Details

Reaction catalysed: 
[Pyruvate dehydrogenase (acetyl-transferring)] phosphate + H(2)O = [pyruvate dehydrogenase (acetyl-transferring)] + phosphate
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-153031 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial Chain: A
Molecule details ›
Chain: A
Length: 467 amino acids
Theoretical weight: 52.68 KDa
Source organism: Bos taurus
Expression system: Escherichia coli
UniProt:
  • Canonical: P35816 (Residues: 72-538; Coverage: 87%)
Gene names: PDP, PDP1, PPM2C
Sequence domains: Protein phosphatase 2C
Structure domains: PPM-type phosphatase domain

Ligands and Environments

1 bound ligand:
Ligand MN 2 x MN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P3221
Unit cell:
a: 75.274Å b: 75.274Å c: 172.637Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.227 0.224 0.284
Expression system: Escherichia coli

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