Assemblies
Assembly Name:
Hydroxymethylglutaryl-CoA lyase, mitochondrial
Multimeric state:
homo dimer
Accessible surface area:
21837.09 Å2
Buried surface area:
3117.44 Å2
Dissociation area:
1,245.08
Å2
Dissociation energy (ΔGdiss):
7.12
kcal/mol
Dissociation entropy (TΔSdiss):
13.29
kcal/mol
Symmetry number:
2
PDBe Complex ID:
PDB-CPX-153052
Assembly Name:
Hydroxymethylglutaryl-CoA lyase, mitochondrial
Multimeric state:
homo dimer
Accessible surface area:
22097.54 Å2
Buried surface area:
2520.39 Å2
Dissociation area:
1,157.6
Å2
Dissociation energy (ΔGdiss):
5.22
kcal/mol
Dissociation entropy (TΔSdiss):
13.22
kcal/mol
Symmetry number:
2
PDBe Complex ID:
PDB-CPX-153052
Assembly Name:
Hydroxymethylglutaryl-CoA lyase, mitochondrial
Multimeric state:
homo dimer
Accessible surface area:
22312.84 Å2
Buried surface area:
2633.67 Å2
Dissociation area:
1,211.72
Å2
Dissociation energy (ΔGdiss):
4.91
kcal/mol
Dissociation entropy (TΔSdiss):
13.26
kcal/mol
Symmetry number:
2
PDBe Complex ID:
PDB-CPX-153052
Macromolecules
Chains: A, B, C, D, E, F
Length: 298 amino acids
Theoretical weight: 31.58 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Pfam: HMGL-like
InterPro:
Length: 298 amino acids
Theoretical weight: 31.58 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P35914 (Residues: 28-325; Coverage: 92%)
Pfam: HMGL-like
InterPro:
- Aldolase-type TIM barrel
- HMG-CoA lyase
- Pyruvate carboxyltransferase
- Hydroxymethylglutaryl-CoA lyase, active site
