PDBe 3mmy

X-ray diffraction
1.65Å resolution

Structural and functional analysis of the interaction between the nucleoporin Nup98 and the mRNA export factor Rae1

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
mRNA export factor Chains: A, C, E, G
Molecule details ›
Chains: A, C, E, G
Length: 368 amino acids
Theoretical weight: 41.02 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P78406 (Residues: 1-368; Coverage: 100%)
Gene names: MRNP41, RAE1
Sequence domains: WD domain, G-beta repeat
Structure domains: YVTN repeat-like/Quinoprotein amine dehydrogenase
Nuclear pore complex protein Nup98 Chains: B, D, F, H
Molecule details ›
Chains: B, D, F, H
Length: 56 amino acids
Theoretical weight: 6.27 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P52948 (Residues: 158-213; Coverage: 3%)
Gene names: ADAR2, NUP98
Structure domains: Arc Repressor Mutant, subunit A

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-B
Spacegroup: P1
Unit cell:
a: 56.396Å b: 79.298Å c: 93.407Å
α: 76.63° β: 89.96° γ: 89.94°
R-values:
R R work R free
0.208 0.206 0.237
Expression system: Spodoptera frugiperda