PDBe 3ml5

X-ray diffraction
2.05Å resolution

Crystal structure of the C183S/C217S mutant of human CA VII in complex with acetazolamide


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Carbonic anhydrase 7 Chain: A
Molecule details ›
Chain: A
Length: 269 amino acids
Theoretical weight: 30.11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P43166 (Residues: 1-264; Coverage: 100%)
Gene name: CA7
Sequence domains: Eukaryotic-type carbonic anhydrase
Structure domains: Carbonic Anhydrase II

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ELETTRA BEAMLINE 5.2R
Spacegroup: P21
Unit cell:
a: 43.78Å b: 66.28Å c: 46.46Å
α: 90° β: 113.84° γ: 90°
R R work R free
0.166 0.166 0.207
Expression system: Escherichia coli