Articles - 3mhc mentioned but not cited (2)
- Pyridinium derivatives of 3-aminobenzenesulfonamide are nanomolar-potent inhibitors of tumor-expressed carbonic anhydrase isozymes CA IX and CA XII. Akocak S, Güzel-Akdemir Ö, Kishore Kumar Sanku R, Russom SS, Iorga BI, Supuran CT, Ilies MA. Bioorg Chem 103 104204 (2020)
- Benchmark Sets for Binding Hot Spot Identification in Fragment-Based Ligand Discovery. Wakefield AE, Yueh C, Beglov D, Castilho MS, Kozakov D, Keserű GM, Whitty A, Vajda S. J Chem Inf Model 60 6612-6623 (2020)
Reviews citing this publication (10)
- An overview of the alpha-, beta- and gamma-carbonic anhydrases from Bacteria: can bacterial carbonic anhydrases shed new light on evolution of bacteria? Capasso C, Supuran CT. J Enzyme Inhib Med Chem 30 325-332 (2015)
- Bacterial, fungal and protozoan carbonic anhydrases as drug targets. Capasso C, Supuran CT. Expert Opin Ther Targets 19 1689-1704 (2015)
- Exploiting the hydrophobic and hydrophilic binding sites for designing carbonic anhydrase inhibitors. De Simone G, Alterio V, Supuran CT. Expert Opin Drug Discov 8 793-810 (2013)
- The many faces of the adamantyl group in drug design. Liu J, Obando D, Liao V, Lifa T, Codd R. Eur J Med Chem 46 1949-1963 (2011)
- Thiadiazole-a promising structure in medicinal chemistry. Li Y, Geng J, Liu Y, Yu S, Zhao G. ChemMedChem 8 27-41 (2013)
- Reconsidering anion inhibitors in the general context of drug design studies of modulators of activity of the classical enzyme carbonic anhydrase. Nocentini A, Angeli A, Carta F, Winum JY, Zalubovskis R, Carradori S, Capasso C, Donald WA, Supuran CT. J Enzyme Inhib Med Chem 36 561-580 (2021)
- Carbonic Anhydrase Inhibitors Targeting Metabolism and Tumor Microenvironment. Angeli A, Carta F, Nocentini A, Winum JY, Zalubovskis R, Akdemir A, Onnis V, Eldehna WM, Capasso C, Simone G, Monti SM, Carradori S, Donald WA, Dedhar S, Supuran CT. Metabolites 10 E412 (2020)
- 1,3,4-Thiadiazoles: a potent multi targeted pharmacological scaffold. Haider S, Alam MS, Hamid H. Eur J Med Chem 92 156-177 (2015)
- Crystallography and Its Impact on Carbonic Anhydrase Research. Lomelino CL, Andring JT, McKenna R. Int J Med Chem 2018 9419521 (2018)
- Thermodynamic, kinetic, and structural parameterization of human carbonic anhydrase interactions toward enhanced inhibitor design. Linkuvienė V, Zubrienė A, Manakova E, Petrauskas V, Baranauskienė L, Zakšauskas A, Smirnov A, Gražulis S, Ladbury JE, Matulis D. Q Rev Biophys 51 e10 (2018)
Articles citing this publication (36)
- Dithiocarbamates strongly inhibit carbonic anhydrases and show antiglaucoma action in vivo. Carta F, Aggarwal M, Maresca A, Scozzafava A, McKenna R, Masini E, Supuran CT. J Med Chem 55 1721-1730 (2012)
- Selective hydrophobic pocket binding observed within the carbonic anhydrase II active site accommodate different 4-substituted-ureido-benzenesulfonamides and correlate to inhibitor potency. Pacchiano F, Aggarwal M, Avvaru BS, Robbins AH, Scozzafava A, McKenna R, Supuran CT. Chem Commun (Camb) 46 8371-8373 (2010)
- Dithiocarbamates: a new class of carbonic anhydrase inhibitors. Crystallographic and kinetic investigations. Carta F, Aggarwal M, Maresca A, Scozzafava A, McKenna R, Supuran CT. Chem Commun (Camb) 48 1868-1870 (2012)
- Kinetic and docking studies of phenol-based inhibitors of carbonic anhydrase isoforms I, II, IX and XII evidence a new binding mode within the enzyme active site. Durdagi S, Şentürk M, Ekinci D, Balaydın HT, Göksu S, Küfrevioğlu Öİ, Innocenti A, Scozzafava A, Supuran CT. Bioorg Med Chem 19 1381-1389 (2011)
- A class of sulfonamide carbonic anhydrase inhibitors with neuropathic pain modulating effects. Carta F, Di Cesare Mannelli L, Pinard M, Ghelardini C, Scozzafava A, McKenna R, Supuran CT. Bioorg Med Chem 23 1828-1840 (2015)
- Sulfonamides incorporating 1,3,5-triazine moieties selectively and potently inhibit carbonic anhydrase transmembrane isoforms IX, XII and XIV over cytosolic isoforms I and II: Solution and X-ray crystallographic studies. Carta F, Garaj V, Maresca A, Wagner J, Avvaru BS, Robbins AH, Scozzafava A, McKenna R, Supuran CT. Bioorg Med Chem 19 3105-3119 (2011)
- Combining the tail and the ring approaches for obtaining potent and isoform-selective carbonic anhydrase inhibitors: solution and X-ray crystallographic studies. Bozdag M, Ferraroni M, Nuti E, Vullo D, Rossello A, Carta F, Scozzafava A, Supuran CT. Bioorg Med Chem 22 334-340 (2014)
- [(Cp-R)M(CO)3] (M=Re or 99mTc) Arylsulfonamide, arylsulfamide, and arylsulfamate conjugates for selective targeting of human carbonic anhydrase IX. Can D, Spingler B, Schmutz P, Mendes F, Raposinho P, Fernandes C, Carta F, Innocenti A, Santos I, Supuran CT, Alberto R. Angew Chem Int Ed Engl 51 3354-3357 (2012)
- Conformational variability of different sulfonamide inhibitors with thienyl-acetamido moieties attributes to differential binding in the active site of cytosolic human carbonic anhydrase isoforms. Biswas S, Aggarwal M, Güzel Ö, Scozzafava A, McKenna R, Supuran CT. Bioorg Med Chem 19 3732-3738 (2011)
- Protonography, a technique applicable for the analysis of η-carbonic anhydrase activity. Del Prete S, De Luca V, Supuran CT, Capasso C. J Enzyme Inhib Med Chem 30 920-924 (2015)
- Biochemical characterization of the γ-carbonic anhydrase from the oral pathogen Porphyromonas gingivalis, PgiCA. Del Prete S, De Luca V, Vullo D, Scozzafava A, Carginale V, Supuran CT, Capasso C. J Enzyme Inhib Med Chem 29 532-537 (2014)
- Inhibition studies of the β-carbonic anhydrases from the bacterial pathogen Salmonella enterica serovar Typhimurium with sulfonamides and sulfamates. Nishimori I, Minakuchi T, Vullo D, Scozzafava A, Supuran CT. Bioorg Med Chem 19 5023-5030 (2011)
- Salen and tetrahydrosalen derivatives act as effective inhibitors of the tumor-associated carbonic anhydrase XII--a new scaffold for designing isoform-selective inhibitors. Carradori S, De Monte C, D'Ascenzio M, Secci D, Celik G, Ceruso M, Vullo D, Scozzafava A, Supuran CT. Bioorg Med Chem Lett 23 6759-6763 (2013)
- Polypharmacology of sulfonamides: pazopanib, a multitargeted receptor tyrosine kinase inhibitor in clinical use, potently inhibits several mammalian carbonic anhydrases. Winum JY, Maresca A, Carta F, Scozzafava A, Supuran CT. Chem Commun (Camb) 48 8177-8179 (2012)
- Inhibition of mammalian carbonic anhydrases I-XIV with grayanotoxin III: solution and in silico studies. Durdagi S, Scozzafava G, Vullo D, Sahin H, Kolayli S, Supuran CT. J Enzyme Inhib Med Chem 29 469-475 (2014)
- Mono-/dihydroxybenzoic acid esters and phenol pyridinium derivatives as inhibitors of the mammalian carbonic anhydrase isoforms I, II, VII, IX, XII and XIV. Carta F, Vullo D, Maresca A, Scozzafava A, Supuran CT. Bioorg Med Chem 21 1564-1569 (2013)
- Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic cyanobacterium Nostoc commune. Vullo D, De Luca V, Del Prete S, Carginale V, Scozzafava A, Capasso C, Supuran CT. Bioorg Med Chem 23 1728-1734 (2015)
- Synthesis of 4-(thiazol-2-ylamino)-benzenesulfonamides with carbonic anhydrase I, II and IX inhibitory activity and cytotoxic effects against breast cancer cell lines. Abdel Gawad NM, Amin NH, Elsaadi MT, Mohamed FMM, Angeli A, De Luca V, Capasso C, Supuran CT. Bioorg Med Chem 24 3043-3051 (2016)
- A class of 4-sulfamoylphenyl-ω-aminoalkyl ethers with effective carbonic anhydrase inhibitory action and antiglaucoma effects. Bozdag M, Pinard M, Carta F, Masini E, Scozzafava A, McKenna R, Supuran CT. J Med Chem 57 9673-9686 (2014)
- Carbonic Anhydrase Inhibition with Benzenesulfonamides and Tetrafluorobenzenesulfonamides Obtained via Click Chemistry. Pala N, Micheletto L, Sechi M, Aggarwal M, Carta F, McKenna R, Supuran CT. ACS Med Chem Lett 5 927-930 (2014)
- Synthesis and crystallographic analysis of new sulfonamides incorporating NO-donating moieties with potent antiglaucoma action. Mincione F, Benedini F, Biondi S, Cecchi A, Temperini C, Formicola G, Pacileo I, Scozzafava A, Masini E, Supuran CT. Bioorg Med Chem Lett 21 3216-3221 (2011)
- Synthesis of a new series of dithiocarbamates with effective human carbonic anhydrase inhibitory activity and antiglaucoma action. Bozdag M, Carta F, Vullo D, Akdemir A, Isik S, Lanzi C, Scozzafava A, Masini E, Supuran CT. Bioorg Med Chem 23 2368-2376 (2015)
- Inhibition of β-carbonic anhydrases with ureido-substituted benzenesulfonamides. Pacchiano F, Carta F, Vullo D, Scozzafava A, Supuran CT. Bioorg Med Chem Lett 21 102-105 (2011)
- Carbonic anhydrase inhibitory activity of sulfonamides and carboxylic acids incorporating cyclic imide scaffolds. Abdel-Aziz AA, El-Azab AS, Ceruso M, Supuran CT. Bioorg Med Chem Lett 24 5185-5189 (2014)
- Cloning, characterization and anion inhibition studies of a new γ-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis. De Luca V, Vullo D, Del Prete S, Carginale V, Scozzafava A, Osman SM, AlOthman Z, Supuran CT, Capasso C. Bioorg Med Chem 23 4405-4409 (2015)
- Inhibition of tumor-associated human carbonic anhydrase isozymes IX and XII by a new class of substituted-phenylacetamido aromatic sulfonamides. Akdemir A, Güzel-Akdemir O, Scozzafava A, Capasso C, Supuran CT. Bioorg Med Chem 21 5228-5232 (2013)
- Effect of incorporating a thiophene tail in the scaffold of acetazolamide on the inhibition of human carbonic anhydrase isoforms I, II, IX and XII. Biswas S, McKenna R, Supuran CT. Bioorg Med Chem Lett 23 5646-5649 (2013)
- Synthesis of sulfonamides incorporating piperazinyl-ureido moieties and their carbonic anhydrase I, II, IX and XII inhibitory activity. Congiu C, Onnis V, Deplano A, Balboni G, Dedeoglu N, Supuran CT. Bioorg Med Chem Lett 25 3850-3853 (2015)
- Design, synthesis and biological evaluation of N-(5-methyl-isoxazol-3-yl/1,3,4-thiadiazol-2-yl)-4-(3-substitutedphenylureido) benzenesulfonamides as human carbonic anhydrase isoenzymes I, II, VII and XII inhibitors. Mishra CB, Kumari S, Angeli A, Monti SM, Buonanno M, Prakash A, Tiwari M, Supuran CT. J Enzyme Inhib Med Chem 31 174-179 (2016)
- Structural effect of phenyl ring compared to thiadiazole based adamantyl-sulfonamides on carbonic anhydrase inhibition. Biswas S, Carta F, Scozzafava A, McKenna R, Supuran CT. Bioorg Med Chem 21 2314-2318 (2013)
- 5-Substituted-benzylsulfanyl-thiophene-2-sulfonamides with effective carbonic anhydrase inhibitory activity: Solution and crystallographic investigations. Ivanova J, Balode A, Žalubovskis R, Leitans J, Kazaks A, Vullo D, Tars K, Supuran CT. Bioorg Med Chem 25 857-863 (2017)
- A failed tentative to design a super carbonic anhydrase having the biochemical properties of the most thermostable CA (SspCA) and the fastest (SazCA) enzymes. De Luca V, Del Prete S, Carginale V, Vullo D, Supuran CT, Capasso C. J Enzyme Inhib Med Chem 30 989-994 (2015)
- Letter Discovery of new potent inhibitors for carbonic anhydrase IX by structure-based virtual screening. Wang L, Yang C, Lu W, Liu L, Gao R, Liao S, Zhao Z, Zhu L, Xu Y, Li H, Huang J, Zhu W. Bioorg Med Chem Lett 23 3496-3499 (2013)
- Structural study of the location of the phenyl tail of benzene sulfonamides and the effect on human carbonic anhydrase inhibition. Güzel-Akdemir O, Biswas S, Lastra K, McKenna R, Supuran CT. Bioorg Med Chem 21 6674-6680 (2013)
- Cloning, characterization and sulfonamide inhibition studies of an α-carbonic anhydrase from the living fossil sponge Astrosclera willeyana. Ohradanova A, Vullo D, Pastorekova S, Pastorek J, Jackson DJ, Wörheide G, Supuran CT. Bioorg Med Chem 20 1403-1410 (2012)
- Mutation of active site residues Asn67 to Ile, Gln92 to Val and Leu204 to Ser in human carbonic anhydrase II: influences on the catalytic activity and affinity for inhibitors. Turkoglu S, Maresca A, Alper M, Kockar F, Işık S, Sinan S, Ozensoy O, Arslan O, Supuran CT. Bioorg Med Chem 20 2208-2213 (2012)