› 3mdo

X-ray diffraction
1.91Å resolution

Crystal structure of a Putative phosphoribosylformylglycinamidine cyclo-ligase (BDI_2101) from Parabacteroides distasonis ATCC 8503 at 1.91 A resolution

Released:
DOI: 10.2210/pdb3mdo/pdb
PDB entry 3mdo coloured by chain, front view.
PDB entry 3mdo coloured by chain, side view.
PDB entry 3mdo coloured by chain, top view.
Source organism: Parabacteroides distasonis ATCC 8503
Entry author: Joint Center for Structural Genomics (JCSG)

Function and Biology Details

Reaction catalysed: 
ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-107943 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phosphoribosylformylglycinamidine cyclo-ligase Chains: A, B
Molecule details ›
Chains: A, B
Length: 389 amino acids
Theoretical weight: 43.21 KDa
Source organism: Parabacteroides distasonis ATCC 8503
Expression system: Escherichia coli
UniProt:
  • Canonical: A6LDR8 (Residues: 1-388; Coverage: 100%)
Gene name: BDI_2101
Sequence domains:
Structure domains:

Ligands and Environments

8 bound ligands:
Ligand CA 7 x CA
Ligand CL 4 x CL
Ligand ACT 2 x ACT
Ligand PEG 11 x PEG
Ligand PGE 5 x PGE
Ligand P6G 1 x P6G
Ligand CAC 1 x CAC
Ligand PG4 2 x PG4
1 modified residue:
Ligand MSE 26 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: P41212
Unit cell:
a: 99.945Å b: 99.945Å c: 163.02Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.156 0.154 0.19
Expression system: Escherichia coli

Quick links