PDBe 3m5t

X-ray diffraction
1.95Å resolution

Fragment tethered to Carbonic Anhydrase II H64C mutant

Source organism: Homo sapiens
Entry authors: Schulze Wischeler J, Heine A, Klebe G

Function and Biology Details

Reaction catalysed:
H(2)CO(3) = CO(2) + H(2)O
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Carbonic anhydrase 2 Chain: A
Molecule details ›
Chain: A
Length: 265 amino acids
Theoretical weight: 29.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P00918 (Residues: 1-260; Coverage: 100%)
Gene name: CA2
Sequence domains: Eukaryotic-type carbonic anhydrase
Structure domains: Carbonic Anhydrase II

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: OTHER
Spacegroup: P21
Unit cell:
a: 42.8Å b: 41.3Å c: 72.1Å
α: 90° β: 104.3° γ: 90°
R R work R free
0.178 0.164 0.25
Expression system: Escherichia coli