PDBe 3l9p

X-ray diffraction
1.8Å resolution

Crystal Structure of the Anaplastic Lymphoma Kinase Catalytic Domain

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ALK tyrosine kinase receptor Chain: A
Molecule details ›
Chain: A
Length: 367 amino acids
Theoretical weight: 41.62 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q9UM73 (Residues: 1072-1410; Coverage: 21%)
Gene name: ALK
Sequence domains: Protein tyrosine kinase
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.3
Spacegroup: P212121
Unit cell:
a: 52.058Å b: 56.904Å c: 103.607Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.192 0.19 0.226
Expression system: Spodoptera frugiperda