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Crystal structure of adaptor protein complex 4 (AP-4) mu4 subunit C-terminal domain, in complex with a sorting peptide from the amyloid precursor protein (APP)

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: vesicle-mediated transport
Cellular component: clathrin adaptor complex

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GO terms

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF00928
Domain description: Adaptor complexes medium subunit family
Occurring in:
  1. AP-4 complex subunit mu-1
The deposited structure of PDB entry 3l81 contains 1 copy of Pfam domain PF00928 (Adaptor complexes medium subunit family) in AP-4 complex subunit mu-1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001392
Domain description: Clathrin adaptor, mu subunit
Occurring in:
  1. AP-4 complex subunit mu-1
IPR028565
Domain description: Mu homology domain
Occurring in:
  1. AP-4 complex subunit mu-1
IPR018240
Domain description: Clathrin adaptor, mu subunit, conserved site
Occurring in:
  1. AP-4 complex subunit mu-1
IPR036168
Domain description: AP-2 complex subunit mu, C-terminal superfamily
Occurring in:
  1. AP-4 complex subunit mu-1

Structure domain

CATH CATH domain
2.60.40.1170
Class: Mainly Beta
Architecture: Sandwich
Topology: Immunoglobulin-like
Homology: Mu homology domain, subdomain B
Occurring in:
  1. AP-4 complex subunit mu-1
The deposited structure of PDB entry 3l81 contains 2 copies of CATH domain 2.60.40.1170 (Immunoglobulin-like) in AP-4 complex subunit mu-1. Showing 2 copies in chain A.

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