Structure analysis

Structure of MHC class II molecule HLA-DR1 complexed with phosphopeptide MART-1

X-ray diffraction
2.1Å resolution
Source organism: Homo sapiens
Assembly composition:
hetero trimer (preferred)
Entry contents: 3 distinct polypeptide molecules


Assembly 1 (preferred)
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Multimeric state: hetero trimer
Accessible surface area: 17800 Å2
Buried surface area: 7600 Å2
Dissociation area: 1,200 Å2
Dissociation energy (ΔGdiss): 13 kcal/mol
Dissociation entropy (TΔSdiss): 9 kcal/mol
Interface energy (ΔGint): -41 kcal/mol
Symmetry number: 1


Chain: C
Length: 15 amino acids
Theoretical weight: 1.67 KDa
Source organism: Homo sapiens
Expression system: Not provided
  • Canonical: Q16655 (Residues: 100-114; Coverage: 13%)
Gene names: MART1, MLANA

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