› › Structure analysis

Staphylococcal Complement Inhibitor (SCIN) in complex with Human Complement Component C3b

X-ray diffraction
7.536Å resolution
PDB entry 3l5n coloured by chain, front view.
PDB entry 3l5n coloured by chain, side view.
PDB entry 3l5n coloured by chain, top view.
Source organisms:
Assembly composition:
hetero trimer (preferred)
Entry contents: 3 distinct polypeptide molecules

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Complement C3b complex and Staphylococcal complement inhibitor
hide full assembly name
Multimeric state: hetero trimer
Accessible surface area: 74328.98 Å2
Buried surface area: 13031.06 Å2
Dissociation area: 902.99 Å2
Dissociation energy (ΔGdiss): -4.38 kcal/mol
Dissociation entropy (TΔSdiss): 12.09 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-133834

Macromolecules

Complement C3 beta chain
Chain: A
Length: 645 amino acids
Theoretical weight: 71.39 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P01024 (Residues: 23-667; Coverage: 39%)
Gene names: C3, CPAMD1
Pfam:
InterPro:
Complement C3 beta chain in PDB entry 3l5n, assembly 1, front view.
Complement C3 beta chain in PDB entry 3l5n, assembly 1, side view.
Complement C3 beta chain in PDB entry 3l5n, assembly 1, top view.
Molecule details ›

Search similar proteins

Complement C3b alpha' chain
Chain: B
Length: 915 amino acids
Theoretical weight: 104.07 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P01024 (Residues: 749-1663; Coverage: 56%)
Gene names: C3, CPAMD1
Pfam:
InterPro:
Complement C3b alpha' chain in PDB entry 3l5n, assembly 1, front view.
Complement C3b alpha' chain in PDB entry 3l5n, assembly 1, side view.
Complement C3b alpha' chain in PDB entry 3l5n, assembly 1, top view.
Molecule details ›

Search similar proteins

Staphylococcal complement inhibitor
Chain: M
Length: 88 amino acids
Theoretical weight: 10.06 KDa
Source organism: Staphylococcus aureus subsp. aureus Mu50
Expression system: Escherichia coli
UniProt:
  • Canonical: Q931M7 (Residues: 32-116; Coverage: 100%)
Gene names: SAV1942, scn
Pfam: Staphylococcal complement inhibitor SCIN
InterPro:
Staphylococcal complement inhibitor in PDB entry 3l5n, assembly 1, front view.
Staphylococcal complement inhibitor in PDB entry 3l5n, assembly 1, side view.
Staphylococcal complement inhibitor in PDB entry 3l5n, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links