PDBe 3l5j

X-ray diffraction
3.04Å resolution

Crystal structure of FnIII domains of human GP130 (Domains 4-6)

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Interleukin-6 receptor subunit beta Chains: A, B
Molecule details ›
Chains: A, B
Length: 288 amino acids
Theoretical weight: 32.67 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P40189 (Residues: 323-610; Coverage: 32%)
Gene name: IL6ST
Sequence domains: Fibronectin type III domain
Structure domains: Immunoglobulins

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX1
Spacegroup: C2
Unit cell:
a: 102.936Å b: 89.221Å c: 106.877Å
α: 90° β: 117.72° γ: 90°
R-values:
R R work R free
0.213 0.213 0.265
Expression system: Escherichia coli