PDBe 3kz7

X-ray diffraction
1.95Å resolution

C-terminal domain of Murine FKBP25 rapamycin complex

Released:
Source organism: Mus musculus
Primary publication:
Diversified targets of FKBP25 and its complex with rapamycin.
Int. J. Biol. Macromol. 69C 344-352 (2014)
PMID: 24879919

Function and Biology Details

Reaction catalysed:
Peptidylproline (omega=180) = peptidylproline (omega=0). 
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peptidyl-prolyl cis-trans isomerase FKBP3 Chain: A
Molecule details ›
Chain: A
Length: 119 amino acids
Theoretical weight: 13.28 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q62446 (Residues: 106-224; Coverage: 53%)
Gene names: Fkbp25, Fkbp3
Sequence domains: FKBP-type peptidyl-prolyl cis-trans isomerase

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: P41212
Unit cell:
a: 85.649Å b: 85.649Å c: 53.09Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.177 0.175 0.222
Expression system: Escherichia coli