PDBe 3kl8

X-ray diffraction
3.37Å resolution

CaMKIINtide Inhibitor Complex


Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Calcium/calmodulin-dependent protein kinase type II Chains: A, C, E, G, I
Molecule details ›
Chains: A, C, E, G, I
Length: 269 amino acids
Theoretical weight: 30.45 KDa
Source organism: Caenorhabditis elegans
Expression system: Escherichia coli
  • Canonical: O62305 (Residues: 5-273; Coverage: 37%)
Gene names: K11E8.1, unc-43
Sequence domains: Protein kinase domain
Structure domains:
Calcium/calmodulin-dependent protein kinase II inhibitor 1 Chains: B, D, F, H, J
Molecule details ›
Chains: B, D, F, H, J
Length: 18 amino acids
Theoretical weight: 2.01 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
  • Canonical: Q9JI15 (Residues: 42-58; Coverage: 22%)
Gene name: Camk2n1

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.2
Spacegroup: P21
Unit cell:
a: 72.41Å b: 83.08Å c: 145.13Å
α: 90° β: 101.93° γ: 90°
R R work R free
0.234 0.23 0.281
Expression system: Escherichia coli