PDBe 3kgv

X-ray diffraction
6.6Å resolution

Crystal Structure of Human DNA-dependent Protein Kinase Catalytic Subunit (DNA-PKcs)

Released:

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo heptamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA-dependent Protein Kinase Catalytic Subunit Chains: A, B, C, D, E, F, O, P, Q, R, S, T, X, Y
Molecule details ›
Chains: A, B, C, D, E, F, O, P, Q, R, S, T, X, Y
Length: 4128 amino acids
Theoretical weight: 351.34 KDa
Source organism: Homo sapiens

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P21
Unit cell:
a: 168.6Å b: 132.99Å c: 297Å
α: 90° β: 105.58° γ: 90°
R-values:
R R work R free
0.442 0.442 0.441