PDBe 3kb9

X-ray diffraction
1.6Å resolution

Epi-isozizaene synthase: Complex with Mg, inorganic pyrophosphate and benzyl triethyl ammonium cation

Released:

Function and Biology Details

Reaction catalysed:
(2E,6E)-farnesyl diphosphate = (+)-epi-isozizaene + diphosphate. 
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Epi-isozizaene synthase Chain: A
Molecule details ›
Chain: A
Length: 382 amino acids
Theoretical weight: 43.72 KDa
Source organism: Streptomyces coelicolor
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9K499 (Residues: 2-361; Coverage: 100%)
Gene names: SC7E4.19, SCO5222, cyc1
Structure domains: Farnesyl Diphosphate Synthase

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P21
Unit cell:
a: 53.185Å b: 47.374Å c: 75.376Å
α: 90° β: 95.53° γ: 90°
R-values:
R R work R free
0.16 0.158 0.189
Expression system: Escherichia coli