› › Structure analysis

Crystal Structure of TR-alfa bound to the selective thyromimetic TRIAC

X-ray diffraction
2.007Å resolution
PDB entry 3jzb coloured by chain, front view.
PDB entry 3jzb coloured by chain, side view.
PDB entry 3jzb coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Thyroid hormone receptor alpha
hide full assembly name
Multimeric state: monomeric
Accessible surface area: 13046.91 Å2
Buried surface area: 769.89 Å2
Dissociation area: 384.94 Å2
Dissociation energy (ΔGdiss): -2.69 kcal/mol
Dissociation entropy (TΔSdiss): 5.58 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-145479

Macromolecules

Thyroid hormone receptor alpha
Chain: A
Length: 267 amino acids
Theoretical weight: 30.78 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P10827 (Residues: 148-370; Coverage: 46%)
Gene names: EAR7, ERBA1, NR1A1, THRA, THRA1, THRA2
Pfam: Ligand-binding domain of nuclear hormone receptor
InterPro:
CATH: Retinoid X Receptor
Thyroid hormone receptor alpha in PDB entry 3jzb, assembly 1, front view.
Thyroid hormone receptor alpha in PDB entry 3jzb, assembly 1, side view.
Thyroid hormone receptor alpha in PDB entry 3jzb, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links