PDBe 3jxf

X-ray diffraction
2Å resolution

CA-like domain of human PTPRZ

Released:

Function and Biology Details

Reaction catalysed:
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate. 
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Receptor-type tyrosine-protein phosphatase zeta Chains: A, B
Molecule details ›
Chains: A, B
Length: 272 amino acids
Theoretical weight: 30.83 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P23471 (Residues: 34-302; Coverage: 12%)
Gene names: HTPZP2, PTPRZ, PTPRZ1, PTPRZ2, PTPZ
Sequence domains: Eukaryotic-type carbonic anhydrase
Structure domains: Carbonic Anhydrase II

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P21
Unit cell:
a: 63.963Å b: 68.118Å c: 65.682Å
α: 90° β: 98.48° γ: 90°
R-values:
R R work R free
0.177 0.175 0.219
Expression system: Escherichia coli