PDBe 3jtc

X-ray diffraction
1.6Å resolution

Importance of Mg2+ in the Ca2+-Dependent Folding of the gamma-Carboxyglutamic Acid Domains of Vitamin K-Dependent clotting and anticlotting Proteins

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Vitamin K-dependent protein C light chain Chains: C, D
Molecule details ›
Chains: C, D
Length: 33 amino acids
Theoretical weight: 4.36 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P04070 (Residues: 43-75; Coverage: 7%)
Gene name: PROC
Endothelial protein C receptor Chains: A, B
Molecule details ›
Chains: A, B
Length: 193 amino acids
Theoretical weight: 22.05 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9UNN8 (Residues: 18-210; Coverage: 87%)
Gene names: EPCR, PROCR
Structure domains: Murine Class I Major Histocompatibility Complex, H2-DB, subunit A, domain 1

Ligands and Environments


1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: P21
Unit cell:
a: 59.22Å b: 62.36Å c: 71.03Å
α: 90° β: 101.81° γ: 90°
R-values:
R R work R free
0.192 0.191 0.226