› 3j34

Electron Microscopy
8.6Å resolution

Structure of HIV-1 Capsid Protein by Cryo-EM

Released:
DOI: 10.2210/pdb3j34/pdb
PDB entry 3j34 coloured by chain, front view.
PDB entry 3j34 coloured by chain, side view.
PDB entry 3j34 coloured by chain, top view.
Source organism: Human immunodeficiency virus 1
Primary publication:
Mature HIV-1 capsid structure by cryo-electron microscopy and all-atom molecular dynamics.
Zhao G, Perilla JR, Yufenyuy EL, Meng X, Chen B, Ning J, Ahn J, Gronenborn AM, Schulten K, Aiken C, Zhang P
Nature 497 643-6 (2013)
PMID: 23719463
Related structures: EMD-5582

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo 42-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-181245 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Gag protein Chains: 5, 6, 7, A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z, a, b, c, d, e, f, g, h, i, j, k, l, m
Molecule details ›
Chains: 5, 6, 7, A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z, a, b, c, d, e, f, g, h, i, j, k, l, m
Length: 231 amino acids
Theoretical weight: 25.7 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q79791 (Residues: 133-363; Coverage: 46%)
Gene name: gag
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 8.6Å
Relevant EMDB volumes: EMD-5582
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

124 review citations

Single-Particle Cryo-EM at Crystallographic Resolution.
Cheng Y. (2015)
123 more

31 mentions without citation

Molecular Architecture of the Retroviral Capsid.
Perilla et al. (2016)
30 more