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SIVmac239 Nef in complex with TCR zeta ITAM 1 polypeptide (A63-R80)

Source organisms:
Biochemical function: GTP binding
Biological process: not assigned
Cellular component: not assigned

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GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF02189
Domain description: Immunoreceptor tyrosine-based activation motif
Occurring in:
  1. T-cell surface glycoprotein CD3 zeta chain
The deposited structure of PDB entry 3ik5 contains 2 copies of Pfam domain PF02189 (Immunoreceptor tyrosine-based activation motif) in T-cell surface glycoprotein CD3 zeta chain. Showing 1 copy in chain D [auth B].

PF00469
Domain description: Negative factor, (F-Protein) or Nef
Occurring in:
  1. Protein Nef
The deposited structure of PDB entry 3ik5 contains 2 copies of Pfam domain PF00469 (Negative factor, (F-Protein) or Nef) in Protein Nef. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR027481
Domain description: HIV-1 Nef protein, core domain superfamily
Occurring in:
  1. Protein Nef
IPR001558
Domain description: HIV negative factor Nef
Occurring in:
  1. Protein Nef

Structure domain

CATH CATH domain
3.30.62.10
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: Nef Regulatory Factor
Homology: Nef Regulatory Factor
Occurring in:
  1. Protein Nef
The deposited structure of PDB entry 3ik5 contains 2 copies of CATH domain 3.30.62.10 (Nef Regulatory Factor) in Protein Nef. Showing 1 copy in chain A.

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