PDBe 3i2t

X-ray diffraction
2.7Å resolution

Crystal structure of the unliganded Drosophila Epidermal Growth Factor Receptor ectodomain


Function and Biology Details

Structure analysis Details

Assemblies composition:
homo dimer
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Epidermal growth factor receptor Chain: A
Molecule details ›
Chain: A
Length: 551 amino acids
Theoretical weight: 62.45 KDa
Source organism: Drosophila melanogaster
Expression system: Spodoptera frugiperda
  • Canonical: P04412 (Residues: 100-644; Coverage: 39%)
Gene names: CG10079, DER, Egfr, c-erbB, top
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-D
Spacegroup: C2221
Unit cell:
a: 74.378Å b: 174.798Å c: 161.653Å
α: 90° β: 90° γ: 90°
R R work R free
0.228 0.224 0.264
Expression system: Spodoptera frugiperda