EC 3.5.3.18: Dimethylargininase
Reaction catalysed:
N(omega),N(omega)-dimethyl-L-arginine + H(2)O = dimethylamine + L-citrulline
Systematic name:
N(omega),N(omega')-dimethyl-L-arginine dimethylamidohydrolase
Alternative Name(s):
- Dimethylarginine dimethylaminohydrolase
- N(G),N(G)-dimethyl-L-arginine dimethylamidohydrolase
- N(G),N(G)-dimethylarginine dimethylaminohydrolase
- N(omega),N(omega')-methyl-L-arginine dimethylamidohydrolase
- Omega,omega'-di-N-methyl-L-arginine dimethylamidohydrolase
GO terms
Biochemical function:
Biological process:
- negative regulation of cellular response to hypoxia
- nitric oxide metabolic process
- positive regulation of angiogenesis
- positive regulation of nitric oxide biosynthetic process
- negative regulation of vascular permeability
- negative regulation of cell population proliferation
- nitric oxide mediated signal transduction
- arginine catabolic process
- arginine metabolic process
- regulation of systemic arterial blood pressure
- citrulline metabolic process
Protein family (Pfam)
InterPro annotation
CATH domain