PDBe 3hyh

X-ray diffraction
2.2Å resolution

Crystal structure of the protein kinase domain of yeast AMP-activated protein kinase Snf1

Released:
Source organism: Saccharomyces cerevisiae
Primary publication:
Crystal structure of the protein kinase domain of yeast AMP-activated protein kinase Snf1.
Biochem. Biophys. Res. Commun. 337 1224-8 (2005)
PMID: 16236260

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein. 
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Carbon catabolite-derepressing protein kinase Chains: A, B
Molecule details ›
Chains: A, B
Length: 275 amino acids
Theoretical weight: 31.35 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: P06782 (Residues: 41-315; Coverage: 43%)
Gene names: CAT1, CCR1, D8035.20, GLC2, PAS14, SNF1, YDR477W
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4A
Spacegroup: P212121
Unit cell:
a: 71.028Å b: 75.137Å c: 113.699Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.241 0.239 0.28
Expression system: Escherichia coli