PDBe 3hwo

X-ray diffraction
2.3Å resolution

Crystal structure of Escherichia coli enterobactin-specific isochorismate synthase EntC in complex with isochorismate

Released:

Function and Biology Details

Reaction catalysed:
Chorismate = isochorismate
Biochemical function:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Isochorismate synthase EntC Chains: A, B
Molecule details ›
Chains: A, B
Length: 394 amino acids
Theoretical weight: 43.26 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
  • Canonical: P0AEJ2 (Residues: 1-391; Coverage: 100%)
Gene names: JW0585, b0593, entC
Sequence domains: chorismate binding enzyme
Structure domains: Anthranilate synthase

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29, SRS BEAMLINE PX10.1
Spacegroup: P212121
Unit cell:
a: 62.469Å b: 104.795Å c: 140.014Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.203 0.2 0.256
Expression system: Escherichia coli