› 3hn2

X-ray diffraction
2.5Å resolution

Crystal structure of 2-dehydropantoate 2-reductase FROM Geobacter metallireducens GS-15

Released:
DOI: 10.2210/pdb3hn2/pdb
PDB entry 3hn2 coloured by chain, front view.
PDB entry 3hn2 coloured by chain, side view.
PDB entry 3hn2 coloured by chain, top view.
Source organism: Geobacter metallireducens GS-15
Entry authors: Patskovsky Y, Toro R, Morano C, Rutter M, Chang S, Sauder JM, Burley SK, Almo SC, New York SGX Research Center for Structural Genomics (NYSGXRC)

Function and Biology Details

Reaction catalysed: 
(R)-pantoate + NADP(+) = 2-dehydropantoate + NADPH
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-174473 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
2-dehydropantoate 2-reductase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 312 amino acids
Theoretical weight: 34.35 KDa
Source organism: Geobacter metallireducens GS-15
Expression system: Escherichia coli
UniProt:
  • Canonical: Q39SB2 (Residues: 2-302; Coverage: 100%)
Gene names: Gmet_2643, panE
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P212121
Unit cell:
a: 77.318Å b: 82.179Å c: 201.291Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.244 0.243 0.292
Expression system: Escherichia coli

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