› 3hm3

X-ray diffraction
1.96Å resolution

The Structure and conformation of Lys-63 linked tetra-ubiquitin

Released:
DOI: 10.2210/pdb3hm3/pdb
PDB entry 3hm3 coloured by chain, front view.
PDB entry 3hm3 coloured by chain, side view.
PDB entry 3hm3 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The structure and conformation of Lys63-linked tetraubiquitin.
Datta AB, Hura GL, Wolberger C
J Mol Biol 392 1117-24 (2009)
PMID: 19664638

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-143327 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ubiquitin Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 76 amino acids
Theoretical weight: 8.58 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P0CG48 (Residues: 609-684; Coverage: 11%)
Gene name: UBC
Sequence domains: Ubiquitin family
Structure domains: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

Ligands and Environments

1 bound ligand:
Ligand ZN 6 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 14-BM-C
Spacegroup: P213
Unit cell:
a: 105.882Å b: 105.882Å c: 105.882Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.188 0.186 0.236
Expression system: Escherichia coli

Quick links

Citations

19 review citations

The ubiquitin code.
Komander et al. (2012)
18 more

13 mentions without citation

Unraveling the complexity of ubiquitin signaling.
Strieter et al. (2012)
12 more