PDBe 3hdn

X-ray diffraction
3.1Å resolution

Crystal structure of serum and glucocorticoid-regulated kinase 1 in complex with compound 2

Released:

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein. 
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serine/threonine-protein kinase Sgk1 Chain: A
Molecule details ›
Chain: A
Length: 373 amino acids
Theoretical weight: 42.3 KDa
Source organism: Homo sapiens
Expression system: unidentified baculovirus
UniProt:
  • Canonical: O00141 (Residues: 60-431; Coverage: 86%)
Gene names: SGK, SGK1
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P6522
Unit cell:
a: 96.812Å b: 96.812Å c: 150.779Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.251 0.25 0.278
Expression system: unidentified baculovirus