PDBe 3h8v

X-ray diffraction
2Å resolution

Human Ubiquitin-activating Enzyme 5 in Complex with ATP

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ubiquitin-like modifier-activating enzyme 5 Chains: A, B
Molecule details ›
Chains: A, B
Length: 292 amino acids
Theoretical weight: 32.17 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9GZZ9 (Residues: 57-329; Coverage: 68%)
  • Best match: Q9GZZ9-2 (Residues: 1-273)
Gene names: UBA5, UBE1DC1
Structure domains: NAD(P)-binding Rossmann-like Domain

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P3221
Unit cell:
a: 77.999Å b: 77.999Å c: 207.005Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.193 0.191 0.224
Expression system: Escherichia coli BL21(DE3)