Function and Biology Details
Reaction catalysed:
(1a) (2R,3S)-3-isopropylmalate = 2-isopropylmaleate + H(2)O
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
3-isopropylmalate dehydratase small subunit (preferred)
PDBe Complex ID:
PDB-CPX-161730 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
3-isopropylmalate dehydratase small subunit
Molecule details ›
Chains: A, B
Length: 189 amino acids
Theoretical weight: 20.63 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli
UniProt:
Sequence domains: Aconitase C-terminal domain
Structure domains: Aconitase, domain 4
Length: 189 amino acids
Theoretical weight: 20.63 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli
UniProt:
- Canonical:
P9WK95 (Residues: 2-186; Coverage: 93%)
Sequence domains: Aconitase C-terminal domain
Structure domains: Aconitase, domain 4
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
ESRF BEAMLINE ID23-2
Spacegroup:
C2
Expression system: Escherichia coli
