PDBe 3h0i

X-ray diffraction
2.2Å resolution

human Fyn SH3 domain R96I mutant, crystal form II

Released:
Source organism: Homo sapiens
Entry authors: Dumas C, Strub M-P, Arold ST

Function and Biology Details

Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate. 
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tyrosine-protein kinase Fyn Chains: A, B
Molecule details ›
Chains: A, B
Length: 73 amino acids
Theoretical weight: 8.03 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P06241 (Residues: 73-142; Coverage: 13%)
Gene name: FYN
Sequence domains: SH3 domain
Structure domains: SH3 Domains

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P4212
Unit cell:
a: 90.387Å b: 90.387Å c: 26.77Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.187 0.184 0.243
Expression system: Escherichia coli