PDBe 3gws

X-ray diffraction
2.2Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thyroid hormone receptor beta Chain: X
Molecule details ›
Chain: X
Length: 259 amino acids
Theoretical weight: 29.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P10828 (Residues: 202-460; Coverage: 56%)
Gene names: ERBA2, NR1A2, THR1, THRB
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor

Ligands and Environments

1 bound ligand:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU ULTRAX 18
Spacegroup: P3121
Unit cell:
a: 68.974Å b: 68.974Å c: 131.247Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.193 0.191 0.233
Expression system: Escherichia coli