Assemblies
Assembly Name:
Epidermal growth factor receptor and peptide
Multimeric state:
hetero trimer
Accessible surface area:
25594.16 Å2
Buried surface area:
6108.41 Å2
Dissociation area:
437.74
Å2
Dissociation energy (ΔGdiss):
-1.17
kcal/mol
Dissociation entropy (TΔSdiss):
6.42
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-132706
Assembly Name:
Epidermal growth factor receptor
Multimeric state:
homo dimer
Accessible surface area:
26078.28 Å2
Buried surface area:
5157.03 Å2
Dissociation area:
1,577.13
Å2
Dissociation energy (ΔGdiss):
11.15
kcal/mol
Dissociation entropy (TΔSdiss):
13.68
kcal/mol
Symmetry number:
2
PDBe Complex ID:
PDB-CPX-132701
Macromolecules
Chains: A, B, C, D
Length: 330 amino acids
Theoretical weight: 37.62 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Pfam: Protein tyrosine and serine/threonine kinase
InterPro:
Length: 330 amino acids
Theoretical weight: 37.62 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
P00533 (Residues: 696-1022; Coverage: 28%)
Pfam: Protein tyrosine and serine/threonine kinase
InterPro:
- Protein kinase-like domain superfamily
- Protein kinase domain
- Tyrosine-protein kinase, catalytic domain
- Serine-threonine/tyrosine-protein kinase, catalytic domain
- Protein kinase, ATP binding site
- Tyrosine-protein kinase, active site
Chain: X
Length: 11 amino acids
Theoretical weight: 954 Da
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
Length: 11 amino acids
Theoretical weight: 954 Da
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
