PDBe 3gql

X-ray diffraction
2.8Å resolution

Crystal Structure of activated receptor tyrosine kinase in complex with substrates

Released:

Function and Biology Details

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fibroblast growth factor receptor 1 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 326 amino acids
Theoretical weight: 37.29 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P11362 (Residues: 458-774; Coverage: 40%)
Gene names: BFGFR, CEK, FGFBR, FGFR1, FLG, FLT2, HBGFR
Sequence domains: Protein tyrosine kinase
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: C2
Unit cell:
a: 194.168Å b: 78.265Å c: 98.458Å
α: 90° β: 110.55° γ: 90°
R-values:
R R work R free
0.252 0.252 0.289
Expression system: Escherichia coli