› 3g7q

X-ray diffraction
1.8Å resolution

Crystal structure of valine-pyruvate aminotransferase AvtA (NP_462565.1) from Salmonella typhimurium LT2 at 1.80 A resolution

Released:
DOI: 10.2210/pdb3g7q/pdb
PDB entry 3g7q coloured by chain, front view.
PDB entry 3g7q coloured by chain, side view.
PDB entry 3g7q coloured by chain, top view.
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium
Entry author: Joint Center for Structural Genomics (JCSG)

Function and Biology Details

Reaction catalysed: 
L-valine + pyruvate = 3-methyl-2-oxobutanoate + L-alanine
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-187252 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Aminotransferase class I/classII domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 417 amino acids
Theoretical weight: 47.44 KDa
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8ZL86 (Residues: 1-416; Coverage: 100%)
Gene names: STM3665, avtA
Sequence domains: Aminotransferase class I and II
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand CL 3 x CL
Ligand EDO 3 x EDO
1 modified residue:
Ligand MSE 16 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-1
Spacegroup: P6122
Unit cell:
a: 92.28Å b: 92.28Å c: 227.33Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.179 0.178 0.196
Expression system: Escherichia coli

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