Structure analysis

Src Thr338Ile inhibited in the DFG-Asp-Out conformation

X-ray diffraction
2.35Å resolution
Source organism: Gallus gallus
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1
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Multimeric state: monomeric
Accessible surface area: 13600 Å2
Buried surface area: 0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Interface energy (ΔGint): 0 kcal/mol
Symmetry number: 1
Assembly 2 (preferred)
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Multimeric state: monomeric
Accessible surface area: 12900 Å2
Buried surface area: 1300 Å2
Dissociation area: 650 Å2
Dissociation energy (ΔGdiss): 5 kcal/mol
Dissociation entropy (TΔSdiss): 6 kcal/mol
Interface energy (ΔGint): -10 kcal/mol
Symmetry number: 1

Macromolecules

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