PDBe 3g51

X-ray diffraction
1.8Å resolution

Structural diversity of the active conformation of the N-terminal kinase domain of p90 ribosomal S6 kinase 2


Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein. 
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Ribosomal protein S6 kinase alpha-3 Chain: A
Molecule details ›
Chain: A
Length: 325 amino acids
Theoretical weight: 37.48 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
  • Canonical: P18654 (Residues: 44-367; Coverage: 44%)
Gene names: Mapkapk1b, Rps6ka-rs1, Rps6ka3, Rsk2
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: P212121
Unit cell:
a: 51.167Å b: 51.381Å c: 140.873Å
α: 90° β: 90° γ: 90°
R R work R free
0.216 0.204 0.248
Expression system: Escherichia coli