PDBe 3g4i

X-ray diffraction
1.9Å resolution

Crystal structure of human phosphodiesterase 4d with d155871

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
cAMP-specific 3',5'-cyclic phosphodiesterase 4D Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 381 amino acids
Theoretical weight: 43.79 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q08499 (Residues: 380-753; Coverage: 46%)
Gene names: DPDE3, PDE4D
Sequence domains: 3'5'-cyclic nucleotide phosphodiesterase
Structure domains: 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.1
Spacegroup: P212121
Unit cell:
a: 98.865Å b: 113.241Å c: 161.22Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.183 0.181 0.215
Expression system: Spodoptera frugiperda