PDBe 3fzt

X-ray diffraction
1.95Å resolution

Crystal structure of PYK2 complexed with PF-4618433

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein-tyrosine kinase 2-beta Chain: A
Molecule details ›
Chain: A
Length: 277 amino acids
Theoretical weight: 32.19 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q14289 (Residues: 416-692; Coverage: 28%)
Gene names: FAK2, PTK2B, PYK2, RAFTK
Sequence domains: Protein tyrosine kinase
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P212121
Unit cell:
a: 37.713Å b: 82.915Å c: 86.442Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.198 0.196 0.242