PDBe 3fnv

X-ray diffraction
2.1Å resolution

Crystal Structure of Miner1: The Redox-active 2Fe-2S Protein Causative in Wolfram Syndrome 2

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
CDGSH iron-sulfur domain-containing protein 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 83 amino acids
Theoretical weight: 9.49 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8N5K1 (Residues: 57-135; Coverage: 59%)
Gene names: CDGSH2, CISD2, ERIS, ZCD2
Sequence domains: Iron-binding zinc finger CDGSH type
Structure domains: Ribosomal Protein L9; domain 1

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: P212121
Unit cell:
a: 40.904Å b: 48.579Å c: 74.104Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.172 0.17 0.216
Expression system: Escherichia coli